CATIA is widely used throughout the engineering industry, especially in the automotive and aerospace sectors. CATIA V4, CATIA V5, Pro/ENGINEER, NX (formerly Unigraphics), and SolidWorks are the dominant systems.

Aerospace
The Boeing Company used CATIA V3 to develop its 777 airliner, and is currently using CATIA V5 for the 787 series aircraft. They have employed the full range of Dassault Systemes’ 3D PLM products — CATIA, DELMIA, and ENOVIA LCA — supplemented by Boeing developed applications.
European aerospace giant Airbus has been using CATIA since 2001.
Canadian aircraft maker Bombardier Aerospace has done all of its designing on CATIA.

Automotive
Many automotive companies use CATIA to varying degrees, including BMW, Porsche, Daimler Chrysler, Audi, Volkswagen, Bentley Motors Limited, Volvo, Fiat, Benteler AG, PSA Peugeot Citroën, Renault, Toyota, Ford, Scania, Hyundai, Škoda Auto, Tesla Motors, Proton, Tata motors and Mahindra & Mahindra Limited. Goodyear uses it in making tires for automotive and aerospace and also uses a customized CATIA for its design and development. Many automotive companies use CATIA for car structures — door beams, IP supports, bumper beams, roof rails, side rails, body components — because CATIA is very good in surface creation and Computer representation of surfaces.

Shipbuilding
Dassault Systems has begun serving shipbuilders with CATIA V5 release 8, which includes special features useful to shipbuilders. GD Electric Boat used CATIA to design the latest fast attack submarine class for the United States Navy, the Virginia class. Northrop Grumman Newport News also used CATIA to design the Gerald R. Ford class of supercarriers for the US Navy.

Other
Architect Frank Gehry has used the software, through the C-Cubed Virtual Architecture company, now Virtual Build Team, to design his award-winning curvilinear buildings. His technology arm, Gehry Technologies, has been developing software based on CATIA V5 named Digital Project. Digital Project has been used to design buildings and has successfully completed a handful of projects.